methyl 1-methyl-L-histidinate

methyl 1-methyl-L-histidinate - Names and Identifiers

Name	H-His(1-Me)-OMe . HCl
Synonyms	H-His(Nim-Me)-OMe H-His(Nt-Me)-OMeCl H-His(Nτ-Me)-OMe·HCl H-His(1-Me)-OMe . HCl H-His(NT-Me)-OMe.2HCl H-His(1-Me)-OMe hydrochloride methyl 1-methyl-L-histidinate 1-METHYL-L-HISTIDINE METHYL ESTER N'-Methyl-L-Histidine Methyl Ester N'-Methyl-L-histidine methyl ester N-Im-1-Methyl-L-Histidine Methyl Ester Hcl N-tau-Methyl-L-histidine methyl ester hydrochloride (S)-methyl 2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoate hydrochloride
CAS	57519-09-2
InChI	InChI=1/C8H13N3O2/c1-11-4-6(10-5-11)3-7(9)8(12)13-2/h4-5,7H,3,9H2,1-2H3/t7-/m0/s1

methyl 1-methyl-L-histidinate - Physico-chemical Properties

Molecular Formula	C8H13N3O2
Molar Mass	183.21
Density	1.24
Boling Point	347.2±27.0 °C(Predicted)
Flash Point	163.8°C
Solubility	Dichloromethane; Ethyl Acetate; Methanol; Ethanol
Vapor Presure	5.48E-05mmHg at 25°C
pKa	6.62±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.561

methyl 1-methyl-L-histidinate - Introduction

H-His(1-Me)-OMe . HCl is an organic compound with the formula H-His(1-Me)-OMe. HCl. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: White crystal or crystalline powder
-Molecular weight: 227.65g/mol
-Solubility: Soluble in water and alcohol solvents
-Melting point: 170-175°C
-Stability: stable at room temperature, but avoid exposure to light and avoid contact with oxidants

Use:
-Chemical research: H-His(1-Me)-OMe . HCl is commonly used to synthesize and study the interaction of proteins or small molecules with biological macromolecules (such as proteins)
-Drug research and development: It can also be used as an important intermediate or protecting group in the field of drug research and development

Preparation Method:
H-His(1-Me)-OMe . HCl can be prepared by chemical synthesis. The following is a brief step of a synthesis method:
1. First, L-histidine methyl ester is reacted with a methylating agent to obtain a H-His(1-Me)-OMe . HCl intermediate.
2. The intermediate is then reacted with hydrochloric acid to give the final product H-His(1-Me)-OMe. HCl.
The specific chemical reaction conditions and steps may vary according to the specific synthesis method.

Safety Information:
-Dust H-His(1-Me)-OMe . HCl may be irritating to the skin, eyes and respiratory tract and direct contact should be avoided.
-Wear appropriate personal protective equipment such as laboratory gloves, safety glasses and protective masks when used.
-in the operation should pay attention to avoid inhalation of dust, avoid skin contact and eating.
-In case of contact, rinse immediately with plenty of water and seek medical help.
-storage should be sealed in a dry, cool place, away from fire and oxidant.

Please note that different preparation methods and specific uses may require further research and evaluation. When using or preparing H-His(1-Me)-OMe. HCl, please follow the correct laboratory instructions and refer to the relevant safety data sheet and the information provided by the supplier.

Last Update：2024-04-09 21:01:54